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| Total : | £632.48 |
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Lowest Price GuaranteeOrfadin 2 mg is a hard-capsule formulation containing 2mg of nitisinone. The product is manufactured by Swedish Orphan Biovitrum (Sobi) and is available internationally in a 60-capsule bottle. The manufacturer's product information identifies Orfadin as a treatment for hereditary tyrosinemia type 1.
Nitisinone works by inhibiting an enzyme involved in tyrosine metabolism, reducing the formation of toxic metabolites associated with hereditary tyrosinemia type 1. Treatment is used together with dietary restriction of tyrosine and phenylalanine.
Orfadin is used for the treatment of hereditary tyrosinemia type 1 (HT-1), a rare inherited metabolic disorder. Nitisinone treatment reduces the production of harmful metabolites associated with the condition.
It should not be used as a general liver supplement or for routine digestive or nutritional purposes.
Nitisinone treatment requires monitoring of blood tyrosine levels and other clinical parameters because excessive tyrosine can be associated with eye, skin, and neurological complications.
A current Pakistan online listing shows:
The observed Pakistan price is therefore approximately Rs.5,000 for the listed product. The final price may vary according to supplier, pack size, imported stock, availability, and pharmacy.
International product information identifies the standard 2mg presentation as 60 capsules per bottle.
Orfadin is a prescription-only medicine and should only be used under specialist medical supervision.
Pakistan's Drug Regulatory Authority maintains a public registered-product database and pharmaceutical pricing resources for regulated medicines.
