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Tretinoin is a topical form of all-trans retinoic acid and belongs to the retinoid family. It works by increasing skin-cell turnover and helping prevent dead skin cells from accumulating inside pores. This makes it useful in the management of acne, particularly comedonal acne.
In Pakistan, tretinoin cream is sold under different brand names, including Skin A, Retin-A, Acnytret, Airol, Tretinex and others. Drug listings show 0.05% cream formulations among the available products.
Tretinoin can also be prescribed for certain photoaging-related skin concerns. Because it is a potent retinoid and can cause irritation, it should be used according to a dermatologist's or healthcare professional's advice.
Use tretinoin only according to your doctor's or pharmacist's instructions.
Generally, it is applied as a thin layer to clean, completely dry skin. Avoid the eyes, corners of the nose, lips and broken or irritated skin. Do not apply more than recommended because using extra product does not produce faster results and may increase irritation.
During the day, use a broad-spectrum sunscreen because tretinoin can make skin more sensitive to sunlight.
Tretinoin prices vary according to brand, strength, pack size and pharmacy. For example, a current D. Watson listing shows Skin A 0.05% 10g at Rs. 185, while Pakistani drug-price listings show several 0.05% brands with retail prices ranging approximately from Rs. 49 to Rs. 206 depending on brand and pack. A 25g 0.025% imported/dispensed listing is substantially higher at Rs. 2,150.
Observed price range: approximately Rs. 50–2,150, depending heavily on brand, strength and pack size.
Always verify the current price and product strength before purchase.
Tretinoin may initially cause:
Severe or persistent irritation should be discussed with a healthcare professional.



